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Remote won't control music app | SoundLink® Air digital music system
To control iTunes remotely, ensure the feature is enabled in the iTunes settings menu.
Determine if all audio from the computer is being sent to the SoundLink Air.
To resolve this issue, change the Sound Output device in System Preferences menu to something other than SoundLink Air (such as Internal Speakers) then go back to iTunes, send audio to the SoundLink Air and test the remote functionality. Once the Bose system is no longer selected as the audio output device of the computer, iTunes volume and transport controls will work as expected